CORRELATION BETWEEN SARCOPENIA, RISK OF FALLS AND MORTALITY IN THE ELDERLY - SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES

Autores

  • Letícia Prieto Trindade Escola Superior de Ciências da Saúde (ESCS)
  • Alessandra Vidal Prieto Centro Universitário de Brasília (UNICEUB)
  • Rafael Marcos Dias Costa Hospital Santa Luzia – Rede D’or São Luiz
  • Michelly Rodrigues Cavalcante Escola Superior de Ciências da Saúde (ESCS)
  • Inácio Carlos Murta Júnior Escola Superior de Ciências da Saúde (ESCS)
  • Renata Nunes Lima Centro Universitário de Brasília (UNICEUB)
  • Lorrane Azevêdo de Souza Centro Universitário de Brasília (UNICEUB)
  • Fábio Ferreira Amorim Escola Superior de Ciências da Saúde (ESCS)
  • Dilson Palhares Ferreira Escola Superior de Ciências da Saúde (ESCS)

DOI:

https://doi.org/10.25110/arqsaude.v27i10.2023-016

Palavras-chave:

Elderly, Aged, Sarcopenia, Falls, Mortality

Resumo

Introduction: Sarcopenia is a progressive and generalized disorder of the skeletal muscles with multifactorial and complex causes. It involves an accelerated loss of skeletal muscle mass and is associated with increased negative outcomes in older adults, such as functional decline, frailty, falls, and death. Objective: to correlate sarcopenia with the risk of falls and mortality in the elderly. Method: A systematic review of the literature was carried out, considering the publication of observational articles as classified for inclusion. The studies considered eligible were the results of searches in the PubMed, Web of Science, EMBASE and LILACS databases. The descriptors were used for searching. The same descriptors in Portuguese and Spanish provided by DECS (health sciences descriptors) were also included. Results: Of the 922 articles selected, 14 were included in the review. The results were similar in most of the articles identified: there is a positive manifestation between sarcopenia, risk of falls (p < 0.0001) and sarcopenia and mortality (p = 0.009) in the elderly population. Conclusion: It is concluded that sarcopenia is a risk factor for falls and increased general mortality in the elderly.

Referências

AQUIMARA, M. et al. Recomendações para Diagnóstico e Tratamento da Sarcopenia no Brasil. 2020.

BEAUDART, C. et al. Health Outcomes of Sarcopenia: A Systematic Review and Meta-Analysis. PloS one, v. 12, n. 1, p. e0169548, 1 jan. 2017.

BHURCHANDI, S. et al. Correlation of Sarcopenia With Modified Frailty Index as a Predictor of Outcome in Critically Ill Elderly Patients: A Cross-Sectional Study. Cureus, 26 out. 2021.

BORGES, C. L. et al. Quedas E Fatores Associados Entre Idosos Atendidos Em Uma Clínica Escola: Um Estudo De Coorte. Arquivos de Ciências da Saúde da UNIPAR, v. 27, n. 3, p. 1185–1203, 2023.

BUCKINX, F. et al. Prediction of the Incidence of Falls and Deaths Among Elderly Nursing Home Residents: The SENIOR Study. 2017.

BVS MS. Dia Nacional do Idoso e Dia Internacional da Terceira Idade: “A jornada para a igualdade”. Disponível em: <https://bvsms.saude.gov.br/01-10-dia-nacional-do-idoso-e-dia-internacional-da-terceira-idade-a-jornada-para-a-igualdade/>. Acesso em: 4 ago. 2023.

CRUZ-JENTOFT, A. J. et al. Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People. Age and Ageing, v. 39, p. 412–423, 2010.

CUI, M. et al. Impact of sarcopenia on the risk of falls, osteoporosis, fractures, and all causes of death among elderly people: A Meta-analysis of prospective cohort studies. Chinese Journal of Clinical Nutrition, v. 26, n. 5, p. 299–308, 2018.

GADELHA, A. B. et al. Severity of sarcopenia is associated with postural balance and risk of falls in community-dwelling older women. Experimental Aging Research, v. 44, n. 3, p. 258–269, 27 maio 2018a.

GADELHA, A. B. et al. The relationship between muscle quality and incidence of falls in older community-dwelling women: An 18-month follow-up study. Experimental Gerontology, v. 110, p. 241–246, 1 set. 2018b.

HENWOOD, T. et al. Consequences of sarcopenia among nursing home residents at long-term follow-up. 2017.

HERNÁNDEZ-LUIS, R. et al. Prognostic value of physical function tests and muscle mass in elderly hospitalized patients. A prospective observational study. Geriatrics and Gerontology International, v. 18, n. 1, p. 57–64, 1 jan. 2018.

LAM, F. M. H. et al. Cumulative and Incremental Value of Sarcopenia Components on Predicting Adverse Outcomes. Journal of the American Medical Directors Association, v. 21, n. 10, p. 1481- 1489.e3, 1 out. 2020.

LANDI, F. et al. Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clinical Nutrition, v. 31, n. 5, p. 652–658, out. 2012.

LIAO, M. C. et al. Sarcopenia is associated with mortality in non-critical elderly patients visiting the emergency department. Frontiers in Medicine, v. 9, 11 jan. 2023.

MATSUMOTO, H. et al. Sarcopenia is a risk factor for falling in independently living Japanese older adults: A 2-year prospective cohort study of the GAINA study. Geriatrics and Gerontology International, v. 17, n. 11, p. 2124–2130, 1 nov. 2017.

MORLEY, J. E.; ANKER, S. D.; VON HAEHLING, S. Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014. Journal of Cachexia, Sarcopenia and Muscle, v. 5, n. 4, p. 253, 26 nov. 2014.

REIJNIERSE, E. M. et al. Lower skeletal muscle mass at admission independently predicts falls and mortality 3 months post-discharge in hospitalized older patients. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, v. 74, n. 10, p. 1650–1656, 1 out. 2019.

SANTILLI, V. et al. Clinical definition of sarcopenia. Clinical Cases in Mineral and Bone Metabolism, v. 11, n. 3, p. 177–180, 2014.

TANG, T. C. et al. FNIH-defined Sarcopenia Predicts Adverse Outcomes among Community-Dwelling Older People in Taiwan: Results from I-Lan Longitudinal Aging Study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, v. 73, n. 6, p. 828–834, 9 maio 2018.

VERONESE, N. et al. Sarcopenia and health-related outcomes: an umbrella review of observational studies. European Geriatric Medicine, v. 10, n. 6, p. 853–862, 1 dez. 2019.

WARZECHA, M. et al. Relation between risk of falls, sarcopenia and parameters assessing quality of skeletal muscles in a group of postmenopausal women. Przeglad Menopauzalny, v. 19, n. 3, p. 123–129, 2020.

WHO. Relatório Mundial de Envelhecimento. 2015.

WIEDL, A. et al. Prognostic value of orthogeriatric assessment parameters on mortality: a 2 year follow up. 2021.

XU, J. et al. Sarcopenia Is Associated with Mortality in Adults: A Systematic Review and Meta-Analysis. . 1 maio 2022, p. 361–376.

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Publicado

23-10-2023

Como Citar

TRINDADE, Letícia Prieto; PRIETO, Alessandra Vidal; COSTA, Rafael Marcos Dias; CAVALCANTE, Michelly Rodrigues; MURTA JÚNIOR, Inácio Carlos; LIMA, Renata Nunes; DE SOUZA, Lorrane Azevêdo; AMORIM, Fábio Ferreira; FERREIRA, Dilson Palhares. CORRELATION BETWEEN SARCOPENIA, RISK OF FALLS AND MORTALITY IN THE ELDERLY - SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES. Arquivos de Ciências da Saúde da UNIPAR, [S. l.], v. 27, n. 10, p. 5704–5721, 2023. DOI: 10.25110/arqsaude.v27i10.2023-016. Disponível em: https://revistas.unipar.br/index.php/saude/article/view/10759. Acesso em: 22 nov. 2024.

Edição

v. 27 n. 10 (2023)

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